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Investigators at Northwestern University have synthesized a new class of zinc-chelating probes that are useful as ratiometric probes for zinc (Zn(II)). The development of this probe allows the use of a new research reagent to be utilized in the investigation of the functions of zinc in biological s.....
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Lead Inventors: Jason Nieh, Ph.D., Dinesh K SubhravetiProblem or Unmet Need:Process migration, the ability to transfer a process from one computing device to another is a useful facility in distributed computing environments. Its benefits include fault resilience, data access locality, improved syst.....
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Compounds of the invention demonstrate high nAChR subtype selectivityThe 10-cytisine derivatives are significantly more lipophilic than cytisine, and thus more readily penetrate the BBB.
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