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Lead Inventors: Ian LipkinProblem or Unmet Need:Respiratory tract infections may result in a wide spectrum of disease that ranges from minor discomfort to exacerbations of asthma and COPD/emphysema to acute fatal respiratory failure. During an investigation of Influenza-like illness (ILI) using meth..... [更多]
This patented invention discloses methods for identification and compounds found to modulate the PISA receptor and it's downstream immune response. The innate immune system recognizes non-self genetic material and mounts a defensive immune response. However, self cytosolic DNA at times gets targeted..... [更多]
Lead Inventors: Bashir ZikriaProblem or Unmet Need:In sick patients inflammatory signals result in "capillary leak" allowing albumin to leak out of the capillaries into the interstitial space. Historically plasma volume has been measured with iodinated serum albumin and red blood cell (RBC) volume b..... [更多]
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