A series of novel lipid derivatives of phosphonate compounds has been synthesized. These novel compounds have been shown to promote oral uptake and increase delivery of the conjugate to the lung in animal models when compared with the parent compounds. A similar derivatization strategy can also be a.....
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Highly stereoselective and efficient Yields over 90% Exclusive formation of alpha glycolipids Beta glycolipids can also be synthesized in a stereoselective manner Does not require neighboring group participation, eliminates the numerous steps required for the installation and sub.....
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Inhibitors for protein kinasesAnalysis of signal transduction pathwaysTherapeuticsLicenses are available in fields EXCEPT for neurodegenerative disease
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The HOMPS genes represent novel targets for the development of diagnostics and therapeutics for breast and ovarian cancer.
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