Synthetic tag to replace avidin-biotin No competition from endogenous ligands No dissociation after capture Humanized format
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Can be used with high specificity to modulate the talin-integrin beta-sub3 interaction without the side effects that may occur with presently available therapeutic agents and methods. Offers a new screening method to detect agents that block integrin beta-sub3 activation, as well as a method for scr.....
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MSNPs constitute an efficient multifunctional platform with unique advantages in cargo delivery (e.g. DNA/siRNA, small molecule), targeting, controlled release, and bio-imaging. Advantages of using MSNP to deliver siRNA and anticancer drugs include the following: Mesoporous silica .....
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The NPS receptor may be used as a system to assay for agonists that are useful therapeutic agents in narcolepsy, hypersomnia or under conditions when elevated alertness is required. Antagonists to the NPS receptor may also be assayed for novel therapeutic approach to treat insomnia. NPS may also .....
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UC San Diego researchers are patenting a novel approach to pack nucleic acids into polymeric supramolecular nanostructures and render them resistant to nuclease digestion while maintaining sequence selective hybridization competency. This technology is predicated on the idea that steric hindrance th.....
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