New anti-infectives are required now more than ever as resistance to existing drugs increases in prevalence. This pathway is not present in humans and thus is an excellent target for new anti-infective drugs.
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Large scale applications, Ease of Synthesis, Excellent environmental stability
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Megan Sykes, M.D.
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To overcome the challenges of traditional fragment-based drug design, researchers at Purdue University used a combination of computational and experimental technique to discover novel inhibitors of the interaction between proliferating cell nuclear antigen (PCNA) and a peptide that binds to a site o.....
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