BBS is a monoclonal antibody that binds specifically and blocks beta-secretase (BACE1) cleavage site on its substrate, APP. BBS inhibits Ab production, a hall-mark of AD and other neurodegenerative diseases such as ALS.The mechanism of action of BBS is based on binding of the antibody at the cell s.....
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Female mice are fed with diets rich in specific f.a. (saturated or unsaturated) during pregnancy and/or lactation. The offspring is raised on a regular diet or on a fat rich diet, and develops obesity, fatty liver, and insulin resistance, depending on the diet received in utero. The model allows stu.....
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A robust method of identifying moving or changing objects in a video sequence groups each pixel with other adjacent pixels according to either motion or intensity values. Pixels are then repeatedly regrouped into clusters in a hierarchical manner. As these clusters are regrouped, the motion pattern .....
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