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TECHNOLOGYDESCRIPTION:Faculty atthe University of Delaware have developed a method using click chemistry. Specificmolecules and fluorescent dyes are used throughout a designed process. Theseprocesses are carried out over various time periods.  The results allow quantification of variousmetabolic act..... [更多]
Epoxyeicosatrienoic acids (EETs) are lipid metabolites that regulate blood pressure and inflammation. EETs are metabolized by soluble epoxide hydrolase (sEH); therefore, inhibition of sEH may treat hypertension and other medical conditions caused by irregularities in blood pressure, vasodilation, en..... [更多]
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Purdue University researchers have designed and synthesized a novel class of HIV-1 protease inhibitors containing isophthalamide derivatives for the treatment of multidrug-resistant strains of HIV. These potent nonpeptide inhibitors are expected to possess improved pharmacological properties, are ea..... [更多]
Researchers at Purdue University have designed, synthesized, and evaluated a series of exceptionally potent HIV-1 protease inhibitors for the treatment of AIDS and HIV infections. These compounds represent a novel new class of HIV-1 protease inhibitors that include Tp-THF and other substituted ligan..... [更多]
This extensive analysis of the Mardin conflict in southeast Turkey considers the likelihood that socioreligious movements, such as the popular Gülen movement, could effect positive change in ethnoreligious disputes, even those decades old. [更多]
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