Tissuedeterioration can occur due to the accumulation of DNA damage with α-dicarbonylcompounds being key mediators of damage-inducing reactive oxygen species.Unfortunately, they cannot be directly antagonized by antioxidants and only asmall number of biological carbonyl scavengers have been identifi.....
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Docket # 17-3362 Although considerable progress has been made in understanding the genetic basis of morphologic traits (e.g. body size, coat color) in dogs and wolves, the genetic basis of their behavioral divergence is poorly understood. Researchers at Princeton University have conducted a genome-w.....
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Antimicrobial resistance is one of the biggest global health crises we are currently facing, and it is being accelerated by the overuse and misuse of antibiotics. There is a tendency, especially in pediatrics, to prescribe antibiotics for viral infections, or to withhold an antibiotic out of an abun.....
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The Vidalia sweet onion is one of the most popular and successful vegetable crops in the state of Georgia, due largely to its high sugar content and low concentration of pungent sulfur compounds. However, those traits also make the Vidalia onion particularly susceptible to bacterial and fungal infec.....
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ApplicationGeneticengineering of cells of essentially any organism (mammal, bacteria, yeast,fungi, etc.) for the over-production of carboxylic acids and amino acids producedin the TCA cycle. ProblemsAddressed (benefits/advantages)Production of oxaloacetate-derived commodity chemicals viabioferm.....
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