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Inventor: Rex MontgomeryEmeritus Professor of Biochemistryhttp://www.biochem.uiowa.edu/montgomery/index.html [更多]
Neurodegenerative diseases, such as Parkinson’s, Alzheimer’s, and Huntington’s, are characterized by misfolded proteins that aggregate and induce neuronal toxicity and death. Protein disulfide isomerase (PDI) is an enzyme implicated in protein misfolding and has been shown to be upregulated in the b..... [更多]
Though use of renewable energy has become increasingly widespread in recent years, many of these technologies remain dependent on inconstant environmental conditions, resulting in inconsistent energy production. This technology is a water-sensitive bio-hybrid material that expands and contracts in r..... [更多]
System xC- is a cysteine/glutamate antiporter whose inhibition induces ferroptotic cell death. Therapeutic inhibition of system xC- for targeted cell death in certain cancers has previously been stymied by the low potency and poor pharmacokinetics of known inhibitors. This technology identifies the ..... [更多]
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