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Examination of the role of PTEN expression in any mouse model where CRE-recombinase can be conditionally expressed [更多]
Inventionprovides a method for testing drug candidates for the treatment and/orprevention of age related macular degeneration. Specifically, the inventioncomprises an animal model showing drusen development and accumulation, which isneeded to better understand AMD and develop better therapies. Inven..... [更多]
Dr. Mishra’s mouse model;  Mito-OB ® has a specific alteration of prohibitin gene expression in white adipose tissue.  Animals become obese and insulin resistant in a manner analogous to human obesity, diabetes and metabolic syndrome.  Existing mouse obesity molecules are based on appetite dysregula..... [更多]
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