PROTAC technology is emerging as a novel therapeutic method to target diseases caused by the abnormal expression of a disease-causing proteins. PROTACs simultaneously bind a target protein and its E3-ubiquitin ligase, causing ubiquitination and degradation of the target protein. Studying protein-pro.....
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The methods/compositions:ΓÇóEnable differentiation of stem/progenitor cells into oocytes and/or eggsΓÇóCan be applied both ex vivo or in vivo or as a combination to maximize desired outcomesΓÇóProvide a non-invasive procedure to increase oocyte numbers in the ovariesΓÇóAvoid use of potentially harmf.....
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This new system leads to optimal or near-optimal designs with greatly simplified routing architecture. Compared with other methods, it offers: Improved circuit performance due to automatic optimal wire width planning; Better control of performance and area trade-off given the method's flexibility i.....
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Project ID: D2011-33IP Status: Patent Pending U.S and EuropeInvention Description: Novel method to prepare an implantable article comprised of a biocompatible substrate (polymeric or ceramic) to accept a very thin biocompatible, bioactive coating material to facilitate bio-ingrowth between the subst.....
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