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The given technology involves the use of a PTD-DRBD (peptide transduction domain-dsRNA binding protein) fusion peptide. DRBD binds siRNAs with high avidity independent of its sequence and allows PTD-mediated cellular uptake. PTD-DRBD mediated siRNA delivery occurs by a specialized process of macropi..... [更多]
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Useful to search new compounds suppressing neuronal damage in a various conditions.The newly synthesized carbenoxoloneprodrug(Compound B) effectively suppressed glutamate release by activated microglia, and suppressed microglialneruotoxicity. Compound B could ameliorate disease progression of model ..... [更多]
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The tests are the first to predict 6-TP treatment efficacy based on individual genetic informationThe tests are also the first to relate genetic-based immunological traits to 6-TP treatment efficacyThe tests require minimally invasive sample collection from bloodThe genetic assay uses methods amenab..... [更多]
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