Researchers at UC San Diego have introduced micro fabricated electrodes into fluidic channels to facilitate optical detection by controlling and manipulating the positions, angles, and populations of analytes in micro-fluidic channels, such as cells and DNA, via a dielectrophoretic effect. The resea.....
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Matrix metalloproteinases (MMPs) are a class of zinc-dependent hydrolytic enzymes that function in the degradation and restructuring of extracellular proteins. Overexpression of MMPs has been associated with a variety of diseases, including cancer, arthritis, and cardiovascular disease. Commercializ.....
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Improve early diagnosis, help monitor disease progression, provide tools to measure responsiveness to therapy and evaluate the efficiency of islet transplantation and graft survival.
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EPLIN-based molecular reagents will prove useful because there are a limited number of biomarkers with proven utility for detection of breast and prostate cancer. EPLIN-based biomarkers can be used in conjunction with or independently of existing biomarkers to facilitate the diagnosis and prognosis .....
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Potential application to other metastatic epithelial cancers besides bladder and prostate. Antibody therapy can be used alone or in combination with other small molecule inhibitors of mTOR and EGFR. The researchers have experience in developing therapeutic antibodies for previ.....
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