Small (18 amino acids) Non-hemolytic, and virtually noncytotoxic in vitro. Defined mechanism of action against HIV-1 (entry inhibition). Potentially synergistic with other immune-system components, including alpha defensins,protease inhibitors, reverse transcriptase inhibitors, etc.
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Inhibitors for protein kinasesAnalysis of signal transduction pathwaysTherapeuticsLicenses are available in fields EXCEPT for neurodegenerative disease
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Because of its extracellular nature, MAGP-2 can be easily detectable and targetable by antibody-based technologies for example.
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Method of synthesizing Id-KLH is simple and inexpensive Avoids over-conjugation and destruction of critical immunogenic protein motifs Demonstrated superiority of maleimide Id-KLH conjugates over glutaraldehyde Id-KLH conjugates to develop more efficacious vaccines
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