University of California, Irvine researchers have developed a recombinant polynucleotide encoding Her2/neu target antigen. This recombinant polynucleotide contains two regions of the human Her2/neu molecule which demonstrated the lowest degree of homology with other known normal human proteins as t.....
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Simplified scaffold affords the creation of a population of binding proteins with highly diverse binding specificities and affinities through the modification of a single polypeptide chain. Optimized profile of variable residues within the CLec-fold scaffold, which are manipulable without influe.....
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Nitric oxide (NO) is produced in high quantities during sepsis and plays a major role in the development of hypotension. Cobalamin is known from previous studies in animal models to scavenge NO and to reduce mortality from septic shock. Researchers at UCSD have recently discovered that the cobalamin.....
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This new MR/nuclear imaging system diagnoses malignant tumors with high specificity and high sensitivity. The ability to image and detect malignant tumors with both MRI and nuclear imaging techniques may decrease biopsies in patients. Also this imaging system may be used preoperatively in local st.....
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None of the existing treatments for myocardial infarction are as simple as an intravenous perfusion of netrin-1. Current intravenous drugs serve a primarily supportive role, and angioplasty is an invasive procedure.
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