Potential uses of pleiotrophin and related factors include: Kidney growth, morphogenesis, and regeneration in vivo and ex vivo. In vitro engineering of nephrons and artificial kidneys from kidney progenitor cells and embryonic tissues.Repair and regeneration of the injured kidney (eg. acute tubular .....
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Potential application to other metastatic epithelial cancers besides bladder and prostate. Antibody therapy can be used alone or in combination with other small molecule inhibitors of mTOR and EGFR. The researchers have experience in developing therapeutic antibodies for previ.....
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Main Advantages of this InventionΓÇó Effective delivery of the drug through the biological barriersΓÇó No need to chemically alter the drugΓÇó Administered intravenously
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By targeting CSC in specific tumor niches, this invention may present a novel and effective means of treating cells that have evaded eradication by other therapies. Unlike other approaches, this method:accounts for and compensates for the heterogeneity of most tumors;targets cancer stem cells, .....
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The novel GDOX gene may be useful as the basis for novel therapeutics, diagnostics, and prognostics for cancer.Treatment of cancers overexpressing GDOXDetection and monitoring of cancers overexpressing GDOXCancer vaccines based on GDOX antigens
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