In-vivo stability allows for prolonged integrity in systemic circulation. Micellar structure allows delivery of a broad array of payloads, including, magnetic particles, quantum dots, or a therapeutic agent. Reduced cytotoxicity of both hydrophobic drugs and nanoparticle itself. .....
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Through use of the present invention, ineffective treatment regimens can be avoided in certain sub-populations of patients suffering from neoplastic diseases, effective treatment regimens can be instituted for patients who were previously refractive to certain treatments, and an overall improvem.....
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Functional proteins, used in this context, are signal amplifiers since interaction with one molecule of the modulator (designed or natural) leads to binding to, or catalyzing the reaction of, more than one molecule of substrates. The read-out can be a part of any well-established reporting system.....
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Experiments have also been conducted using transgenic mice engineered to mimic the human immune system. The prototype telomerase vaccine induced a CTL response in these mice with no apparent negative side effects, demonstrating the potential of this vaccine in an animal model. Since telomerase is es.....
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The invention provides the following: (1) A new biochemical (FBM) that can be used for research studies; (2) A precursor molecule that can be radiolabeled; (3) An imaging agent that can be used for PET diagnostic imaging of various neurodegenerative disorders including Alzheimer's disease, minimal c.....
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