Main Advantages of this InventionΓÇó Cost-effectiveΓÇó EfficientΓÇó Inert to downstream processes
[更多]
Dendritic cells (DC) are a group of professional antigen presenting cells (APC) that provide a central stimulus for the generation of cell-mediated responses against foreign antigens. Dendritic cells are ubiquitously distributed throughout the body, where they pick up antigens, process them, and mig.....
[更多]
Experiments have also been conducted using transgenic mice engineered to mimic the human immune system. The prototype telomerase vaccine induced a CTL response in these mice with no apparent negative side effects, demonstrating the potential of this vaccine in an animal model. Since telomerase is es.....
[更多]
Rationale: geranylgeranylation of Ras proteins is a key escape pathway for oncogenic cells treated with farnesyl transferase inhibitors (FTIs). Small molecule antagonists of GGTaseI are therefore promising candidates for fully blocking activation of Ras.Leads: Both UC22 and UC23 are drug-like compo.....
[更多]
| |< <- | [40] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] | -> >| |
