It is generally understood that symptoms associated with the menopausal transition (MT) in middle-age women is temporally related to declining ovarian function and the prevailing understanding is that deficits and poor health outcomes related to MT can be prevented and/or are generally resolved by h.....
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Novel, small molecule modulators of endothelial-triggered immune responses. The compounds induce effective immune responses with minimal gene activation, theoretically reducing damaging effects of excessive IFN-γ stimulation.
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The cell penetrating peptides (CPPs) identified in this technology are of shorter length and simpler structure than most known CPPs. Due to these characteristics, these CPPs are more cost effective to produce and are effective in penetrating cell membranes to deliver cargo.
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Predicts efficacy and response of dasatinib therapy on triple negative breast cancer subtypes Genes expressed in patients with specific breast cancer subtypes may be sensitive to therapy with SRC kinase inhibitors Predictive markers may be used in clinical development of compounds to treat solid t.....
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The generation of human induced Pluripotent Stem (iPS) cells holds great promise for development of stem cell therapies to treat a wide range of human diseases. However, the generation of iPS cells in the absence of integrative DNA vectors remains problematic. UCSD researchers have developed a si.....
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