1). Studying neuronal circuit formation and dynamics:? Neurons can be manipulated genetically and mechanically.? Neurons can be assembled into ordered 2D layers and 3D networks.? Beads coated with chemical guidance can cues direct neuronal growth and promote synapse formation.? Network connectivity .....
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Despite the inability of adult CNS to regenerate and the inhibitory environment in the CNS, this method enhances the survival of stem cells that have been grafted into the nervous system, improves functional recovery and alleviates neurological deficits.
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Extremely high throughput: ~28 million cells per second Efficacious at detecting rare cell populations Low cost and convenient Fluorescent or chemical cell labeling is not required
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A screen for P2Y12 using ADP-glucose has been developed. This assay monitors the P2Y12 receptor reactivity in a high-throughput format and thus will lead to the identification of antagonists and/or agonists that are specific to the P2Y12 receptor. Antagonists will mainly target platelet aggregation.....
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