The invention provides a practical, cost-effective method for developing an entirely new product line that fills an unmet market need for a simple test for cancer screening, monitoring prognosis, and predicting progression.The test provides a platform technology to which additional TAA peptides may .....
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Highly specific, inexpensive, non-toxic native binding proteinReduce tumor growth in both subcutaneous and bone cavity environmentsGreater binding spectrum than another BMP-bindng protein, noggin, making it effective for more cancer typesMore is known about the spp24 binding site than that of noggin.....
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Significantly more potent than other commercially available proteasome inhibitors; IC50 values in the low to mid nM range. 3-log specificity for the inhibition of proteasome proteolytic activities as compared to other proteases such as chymotrypsin, trypsin, catharsis A, and catharsis B. W.....
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