None
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Significantly more potent than other commercially available proteasome inhibitors; IC50 values in the low to mid nM range. 3-log specificity for the inhibition of proteasome proteolytic activities as compared to other proteases such as chymotrypsin, trypsin, catharsis A, and catharsis B. W.....
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Highly specific, inexpensive, non-toxic native binding proteinReduce tumor growth in both subcutaneous and bone cavity environmentsGreater binding spectrum than another BMP-bindng protein, noggin, making it effective for more cancer typesMore is known about the spp24 binding site than that of noggin.....
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These are the only nanoparticles known to have dual toxicity to both eukaryotic and prokaryotic cells, with high selectivity. The ability to release drug at sites of interest while tracking the exact location of its delivery using imaging methods employing fluorescence. The shell has bio-toxic activ.....
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Development of more effective therapeutics against human ovarian cancerTreatment for advanced-stage ovarian cancer with recurrent disease or failed first-line chemotherapySuperior safety profile with little to no side effects
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