A chemoselective chemical ligation method is disclosed. The method joins two peptide segments efficiently to produce a larger peptide or protein, by generating a natural peptide bond (Xaa-Ser and Xaa-Thr) at the ligation site (Xaa represents any 5 amino acid). The method requires two steps (Fig. 1 (.....
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Neurotrophins represent a family of proteins which can support the survival and differentiation of neurons from both central and peripheral nervous systems. Their potential use in the treatment of various neurodegenerative diseases is well known. These growth factors exhibit overlapping as well as d.....
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A process for the preparation of carbon layers on powdered supports comprising dissolving a hydrophilic polymer (PH) at the level of 85 do 99.9% by weight in water, adding pyromellitic acid (PMA) or pyromellitic dianhydride (PMDA) at the level of 0.1-15% by weight, then introducing to the mixture th.....
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