Proof of concept and IP is available for compositions of matter, target enzymes, and disease applications for novel relatively unexplored targets for a variety of neurological diseases for which good treatment options do not exist.
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The system is highly flexible. It can:be designed to detect virtually any protease activity of interest;be designed to target proteases located in membranes or vesicles; andaccommodate any measurable reporter protein. The system can be used to observe proteolytic activity in vitro and in vivo in .....
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This polymeric micro-cantilever resonator array has a great potential for achieving unparalleled real-time processing with a high frequency resolution and extremely low power consumption. Their usage in hearing aid and cochlear implant applications should be seriously explored.
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ΓùÅ 17-AAG markedly ameliorated motor phenotypes of the SBMA mouse model without toxicityΓùÅ 17-AGG passes through the blood-brain barrierΓùÅ Hsp90 inhibitors have shown to be effective in animal models of Parkinson disease, stroke and autoimmune encephalomyelitisΓùÅ 17-AAG could be a candidate for .....
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