Inventors at Nationwide Children’s Hospital have developed novel antibody fragments to disrupt biofilms of diverse bacterial species.
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A synergistic increase in apoptosis occurs when myeloproliferative neoplasm primary cells are treated simultaneously with inhibitors of BRD4 and JAK2, and when AML cell lines are treated with inhibitors of BRD4 and FLT3. Moreover, in vitro studies suggest that JAK1/JAK2 inhibitor resistant cells re.....
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This invention provides a new treatment for breast cancer that reduces the risks of side effects that have been observed with treatments currently in use. The novel ceramide analogs of this invention may also be highly effective against: - Highly chemosensitive and chemoresistant forms of breast can.....
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This chitosan derivative may be used to deliver prokaryotic gene silencing CRISPR RNA as a possible treatment for drug resistant infections. Upon acidification, the native chitosan is released. This native chitosan may then damage the bacterial cell membrane and/or interrupt bacterial biological p.....
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These coatings have novel properties with good adhesion, low surface energy and mechanical strength.The invention has potential commercial significance in the paint industry applications related to marine antifouling coatings, anti-graffiti and others.
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