Highlights:The World Health Organisation predicts that by 2040, as a result of a growing ageing population, neurodegenerative diseases (NDDs) will have overtaken cancer to become the world’s second leading cause of death, after cardiovascular disease. However, governments and industry have yet to ma.....
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ER stress, elicited by chemotherapeutic agents such as doxorubicin, 5FU, vincristine and bortezomib, or statins such simvastatin, triggers cell death at least in part through generation of leukotriene C4 (LTC4), which induces ROS accumulation, DNA damage and subsequent cell death. LTC4 can be produc.....
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Interferometry is a method which allows the measurement of very small distances and thicknesses by way of transmitting two beams and using the interference principle (i.e., how they reinforce or neutralize each other) to determine the difference. A problem with interferometry is that it is usually l.....
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New generation of superior nature-inspired therapeutics for treating inflammation.Inflammation is characterized by elevated levels of TNF-?. Neutralizing TNF-? activity was shown to be beneficial for patients with chronic autoimmune inflammatory diseases such as rheumatoid arthritis (RA) and inflamm.....
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