Autophagy is primarily a protective process for the cell, but it can also play a role in cell death. For example, autophagy is vital for embryonic developments, and can prevent cancer cells from spreading while deregulated autophagy was suggested to play a role in autism. Although autophagy is highl.....
[更多]
The invention improves the flow of air around the aft (rear) section of trucks and other heavy road vehicles (such as UAV's). A small add-on device incorporates a novel air flow control valve which generates suction and high frequency oscillations, forcing the air to conform to the shape of the add-.....
[更多]
Need:There is a need for novel compounds with anti-biofilm activity to increase susceptibility of certain bacterial strains towards conventional antibiotics. Innovation:We have developed novel compounds with anti-biofilm activity. We are proposing to use our compounds as a potential anti-biofilm str.....
[更多]
There is a strong need for novel selective and safe approaches for the management of Alzheimer's disease.Development of selective bi-functional small molecules aimed to simultaneously inhibit beta- and gamma secretases in order to reduce amyloid-beta (Aβ) while avoiding toxic effects of full enzymat.....
[更多]
Animal models of human diseases of the CNS occupy a central role in drug discovery yet these models fail to yield new insights and efficacious drugs for the treatment of these diseases, in a field having a collective economic cost of over $40 billion per year. The number of CNS drugs reaching approv.....
[更多]
| |< <- | [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [51] | -> >| |
