AAV can be endowed with robust retrograde functionality through directed evolution Up to two orders of magnitude increase in retrograde transport over existing variants Efficiency comparable to synthetic tracers in many circuits Payload expression levels are sufficient for circuit interrogati.....
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Anti-cancer combination therapy
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10- fold to 100-fold increase in the minimal detection limits for dioxin and related chemicals Dramatically enhanced overall response compared to other bioanalytical methods Rapid and very low cost Mouse, rat and human hepatoma cell lines, stably transfected with the AhR-responsive CA.....
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Array platform allows for multiple targets to be used simultaneously, increases sensitivity and increases speed of diagnosis Ability to bind a vast range of targets in real time Can "communicate" with the innate immune system to induce an immune response without introducing foreign bodies .....
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Early diagnosis Non-invasive therapy Assay-guided therapy/monitoring of therapy and drug response Patient samples are easily obtained in clinic
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