Improve early diagnosis, help monitor disease progression, provide tools to measure responsiveness to therapy and evaluate the efficiency of islet transplantation and graft survival.
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UC San Diego researchers have developed biochemical logic methods and systems for rapid, high-fidelity diagnostics. The invention employs multiple markers as inputs to biochemical logic gates (e.g., “AND” and “XOR”) to trigger a cascade of enzymatic reactions and thus compute a final, digital answer.....
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Researchers at UC San Diego have developed methods for synthesizing and testing a number of novel gamma-secretase modulators with dramatically improved aqueous solubilities. The enhanced aqueous solubilities of these gamma-secretase modulators are expected to exhibit improved pharmacokinetic and.....
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As an illustration of possible applications, described below is one practical example of ESP processing of magnetic resonance diffusion tensor imaging (MR-DTI) data. DTI data is often used for neural fiber tractography in the studies of brain connectivity. This is a complex and severely ill-posed pr.....
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Where current adjuvants act by one or several of the following mechanisms, the Th17-class of adjuvants mediate all of the following: Increase antigen transport and uptake (phagocytosis) by antigen-presenting cells Provide a long-lasting depot effect, i.e., antigenic reservoir .....
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