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AAV10 for Delivery of Therapeutics to Treat ALS and Other CNS Disorders

Detailed Technology Description: AAV10 vector-based gene therapy for treating ALS with enhanced tropism for neuronal cells. Administration of rAAV encoding inhibitory RNA for superoxide dismutase 1 (SOD1) distributes widely throughou

Countries: Not Available

Application No.: None

*Abstract: AAV10 vector-based gene therapy for treating ALS with enhanced tropism for neuronal cells. Administration of rAAV encoding inhibitory RNA for superoxide dismutase 1 (SOD1) distributes widely throughout CNS with low toxicity. Long-term inhibition of mutant SOD1 improves lifespan in the animal models.

*IP Issue Date: None

*IP Type: Other Patent

Country/Region: USA

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