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Methods for Rational Development of Vaccines and Ribotype-Based Speciation

Detailed Technology Description
None
*Abstract
The invention allows for a rapid and inexpensive evaluation of a vaccine target, without resorting to “trial and error” with animal testing. . It determines a statistically significant number of different strains within a species of bacteria indicative of the specific population structure. The invention contemplates the establishment of an initial phylogenic analysis of any bacterial pathogen of interest. With an acccurate phylogenic picture of any particular species of bacteria, one skilled in the art of vaccine target evaluation can proceed with a survey for variability of a large number of possible antigen vaccine target candidates. Thus this method saves enormous time and expense otherwise involved in animal testing.
Country/Region
USA

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