亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

Genetic Test for Equine Immune-Mediated Myositis

技術應用: Genetic testing for horse susceptibility to IMM and nonexertional rhabdomyolysis Diagnosis of IMM in Quarter Horses, Paint Horses and related breeds

詳細技術說明: Immune-mediated myositis (IMM) is a disorder in which the immune system attacks skeletal muscles, causing rapid atrophy of the muscle tissue. IMM is predominantly found in American Quarter Horses and is characterized by rapid-onset muscle atrophy often causing wasting of 40% of the mass of the topline muscles in a matter of days. IMM is responsive to treatment with corticosteroids to halt muscle wasting with return of muscle mass over months. Current diagnosis of IMM in horses involves the measurement of serum creatine kinase and aspartate transaminase, with a definitive diagnosis requiring biopsies of the atrophied rump/back muscles. Researchers at the University of California, Davis and Michigan State University have discovered the genetic mutation for immune-mediate myositis in breeds related to the American Quarter Horse and have created a genetic test for this disease. Horses that are homozygous or heterozygous for the mutation may develop IMM or severe nonexertional rhabdomyolysis. The disease is often triggered by environmental factors such as infection or vaccination in genetically susceptible horses. The mutation is highly associated with the IMM phenotype and can be used with related breeds.This test can be used in breeding stock to minimize the occurrence of IMM.

*Abstract: Researchers at the University of California, Davis and Michigan State University have developed a genetic test to diagnose immune-mediate myositis in American Quarter Horses and related horse breeds.

*Principal Investigation: Name: Carrie Finno
Department:

Name: Stephanie Valberg
Department:

欲了解更多信息，請點擊這裡