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Novel Mithramycin Derivatives for Cancer Chemotherapy (2198)


技術優勢

Key Advantages •     Improved selectivity for betterefficacy and fewer off-target effects•     Potential for less toxicity thanavailable chemotherapeutic agents currently in the clinic•     Better pharmacological propertiesthan current chemotherapies in use today


詳細技術說明

The University of Kentucky is seeking a partner to further develop and commercializevarious mithramycin SA derivatives that were synthesized from a mithramycinSA-producing mutant. The derivatives of particular interest are thosecontaining the dipeptides L-Phe and L-Trp, and provide the potential for moreefficacious and less toxic chemotherapeutic interventions for Ewing’s Sarcoma.


國家/地區

美國

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