Muscle Progenitor Cells Enhance Innervation
A Purdue University researcher has developed a toolkit and a method for repairing and reconstructing a damaged or nonfunctional muscle using in vitro primed muscle progenitor cells to promote innervation of the damaged or nonfunctional muscle without any genetic manipulation. Muscle progenitor cells are harvested and grown to a critical mass in culture. The cells are then injected into the damaged or nonfunctional muscle and fuse with native muscle fiber. Following the injection, the muscle is innervated, atrophy has been shown to reverse, and the muscle fibers have an increased force of contraction.
Does not use genetically modified cells Allows the body to naturally regrow nerve connections Clinically translatable
Innervation Muscle repair Tissue engineering
Stacey HalumThe Voice Clinic of IndianaPurdue Speech, Language, & Hearing Sciences
United States
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美國
