Novel Class of Anti-Estrogens
- 詳細技術說明
- Drs. John and Benita Katzenellenbogen from the University of IL have developed a novel class of anti-estrogen compounds with the potential to act as breast cancer therapeutics.
- *Abstract
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Drs. John and Benita Katzenellenbogen from the University of IL have developed a novel class of anti-estrogen compounds with the potential to act as breast cancer therapeutics. These compounds show potent anti proliferation effects and downregulation of estrogen receptor α. Importantly, these compounds have enhanced bioavailability compared with currently prescribed therapeutics and due to their potency can be administered at lower doses, which minimizes deleterious side effects. Intriguingly, these compounds also show strong binding to various ERα mutants which are common in breast cancer patients.
- *IP Issue Date
- None
- *IP Type
- Other Patent
- 國家
- Not Available
- 申請號碼
- None
- 國家/地區
- 美國
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