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Hair Follicle Stem Cell Activation & Hair Growth by Metabolic Regulators

技術優勢: Topical applicationHigh quality new hair: commercially available treatments produce short, fuzzy hairs that are not like the patients’ typical hair

技術應用: Promote hair growthReduce balding

詳細技術說明: The Lowry group at UCLA has discovered that topical application of a small molecule accelerates the hair cycle and combats hair loss. This drug works by promoting glycolysis in hair follicle stem cells. No other hair loss treatment acts on hair follicle metabolism to promote the hair cycle, and the inventors are the first to show that the activation of hair follicle stem cells is dependent on the production of lactate (a product of glycolysis).

*Abstract: The Lowry group at UCLA has discovered that topical application of a small molecule accelerates hair growth and combats hair loss by promoting glycolytic metabolism in hair follicle stem cells.

*Principal Investigation: Name: Heather Christofk
Department:

Name: William Lowry
Department:

其他

State Of Development

Topical application of the small molecule has been tested in mice and showed a significant increase in hair growth as early as 3-5 days after treatment
Histology analysis confirmed that hair cycle induction by the small molecule was normal in appearance
Research has been completed to understand the mechanism of action

Background

Hair loss is a common, often undesirable symptom of aging. Commercially available products that combat hair thinning or balding have variable efficacy among users. Further, the targets of these products are either unknown or alter hormonal pathways, which may have undesirable side effects. A hair loss remedy that has a higher success rate than current treatments and minimal side effects would greatly increase consumer satisfaction with and usage of hair loss treatments.

Additional Technologies by these Inventors

Tech ID/UC Case

28695/2017-005-0

Related Cases

2017-005-0

國家/地區: 美國

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