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Reactive oxygen species gene signature predicts survival in sepsis

詳細技術說明

Title: Reactive oxygen species gene signature predicts survival in sepsis  Invention: The technology is a 21-gene reactive oxygen species (ROS)-associated molecular signature that predicts survival in septic patients.   Background: Sepsis syndrome’s mortality rate is 26% to 82% depending on whether septic shock occurs. Currently there are no reliable diagnostic biomarkers available to predict survival of patients with sepsis. Furthermore, researchers at the University of Arizona understand there is evidence indicating oxidative stress plays a role in the pathogenesis of sepsis. Applications: Diagnostic tool and/or service for patients with sepsis Advantages: Traditional biomarkers (C-reactive protein, interleukin-6, procalcitonin) are not reliable in predicting survivalROS-associated biomarkers were shown to predict the odds of patient's outcome  Licensing Manager:  Rakhi Gibbons rakhig@tla.arizona.edu(520) 626-6695

*Abstract

None

*Principal Investigation

Name: Louise Hecker, Assistant Professor

Department: Medicine

Name: Marvin Slepian, Professor

Department: Medicine

Name: Christian Bime, Assistant Professor

Department: Medicine

Name: Tong Zhou, Research Assistant Professor

Department: Medicine

Name: Nima Pouladi, Postdoctoral Research Associate I

Department: Medicine

Name: Ting Wang, Assistant Professor

Department: Medicine

國家/地區

美國