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Wirelessly Powered Microfluidic Devices

詳細技術說明
UC San Diego researchers have developed concepts and methods for incorporating printed integrated circuits into microfluidic devices and powering such electronic microfluidic devices wirelessly. In one example, the circuit elements (capacitors, diodes, gates, wires, and electrodes) were roll-to-roll printed on the plastic substrate containing the microfluidic structures and powering was accomplished by wireless coupling from a radio-frequency identification (RFID) reader. On-chip electrophoresis experiments, e.g., fast and effective assembly of microbead arrays and antibodies, have been performed using such a wirelessly powered device. Devices with additional functionality can be fabricated, e.g., with the integration of ring oscillators to generate AC signals for manipulation techniques based on AC-dieletrophoretic effects. Further, with incorporation of cell impedance measurement capability into the device, the data acquired can be sent back to the RFID reader via the printed antenna to realize wireless data transmission and storage.
*Abstract

The last decade has seen tremendous activity in the development of lab-on-a-chip devices utilizing the interaction between suspended biological particles and an electric field. Research groups over the world have fabricated micro- and nano-scaled arrays to demonstrate many functionalities, such as detection, sorting, assembly, and monitoring of mammalian cells, microbeads, bacteria, immunoassay, proteins, DNAs, etc. Microchip-based electrophoresis technology is attractive because of its compact size, parallel architecture, and low cost, which promises higher throughput, faster results, and considerable reduction in the amount of reagents and waste. Despite the technology’s great promise, its acceptance has been slow for clinical applications, such as digital pathology and point-of-care diagnosis. Perhaps the biggest barrier to such acceptance by clinicians is the technology’s requirement of multiple electrical wires between test sample and electronic instruments and configuration for appropriate operation conditions. There has been little effort to remove this barrier.

*IP Issue Date
Jul 17, 2018
*Principal Investigation

Name: Gyiujin Cho

Department:


Name: Yu-Hwa Lo

Department:


Name: Wen Qiao

Department:


Name: Hwiwon Kang

Department:

附加資料
Patent Number: US20140061049A1
Application Number: US13880973A
Inventor: Lo, Yu-Hwa | Qiao, Wen | Cho, Gyoujin | Kang, Hwiwon
Priority Date: 21 Oct 2010
Priority Number: US20140061049A1
Application Date: 15 Nov 2013
Publication Date: 6 Mar 2014
IPC Current: G01N0027447
US Class: 204547 | 204643
Title: MICROFLUIDICS WITH WIRELESSLY POWERED ELECTRONIC CIRCUITS
Usefulness: MICROFLUIDICS WITH WIRELESSLY POWERED ELECTRONIC CIRCUITS
Summary: The microfluidic device is useful for isolating a subpopulation of particles suspended in a fluid (claimed).
Novelty: Microfluidic device useful for isolating a subpopulation of particles suspended in a fluid, comprises a substrate comprising a fluidic channel to provide a path for a fluid with suspended particles, and a pair of electrodes
主要類別
測量/測試
細分類別
測試平台
申請號碼
10024819
其他

Intellectual Property Info

This technology has a patent pending and is available for licensing and/or sponsorship.


Related Materials

Wirelessly Powered Microfluidic Dielectrophoresis Devices Using Printable RF Circuits, Lab Chip, 2011, 11, 1074-1080.


Tech ID/UC Case

21900/2011-085-0


Related Cases

2011-085-0, 2011-113-0

國家/地區
美國

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