亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

LCSC Rat Liver Cell Lines: Cholangiocarcinoma Cell Lines from F344 Rats

*Abstract: Cell Lines Developed From Liver Cancer Cells in Rats
Six cholangiocarcinoma cell lines were developed from F344 rats that had been administered aflatoxin B1 subsequent to liver stem cell mobilization/proliferation. The established rat cell lines, named LCSCs, were immunophenotypically characterized in vitro and their tumorigenicity was assessed in transplant studies. The six cell lines adopted epithelioid morphology, intermingled with small OCT3/4+ cells, and shared with the primary tumors the expression of OV6, CK19, AFP, CD133, cMet, G-CSF and G-CSFR. The transplanted cell lines also appear to incorporate normally into the regenerating recipient livers forming cords of tumor-derived hepatocytes and suggesting the ability to differentiate down the hepatocyte lineage.

*Principal Investigation: Name: Bryon Petersen
Department:

Name: Anna Piscaglia
Department:

Name: Thomas Shupe
Department:

欲了解更多信息，請點擊這裡