Improved Microelectrode Array for Neural Recording
- 標題
- MEMS Flexible Substrate Neural Probe
- 詳細技術說明
- None
- *Abstract
-
Alleviates Strain During Neural Surgery to Minimize Tissue Damage
This neural microelectrode leverages the recording properties of conventional micro-wire electrode arrays with additional features such as the precise control of the electrode geometries and bond pad sites and flexible materials via micromachining. Electrode arrays have high neuronal yield, which improves the accuracy and performance characteristics such as impedance and signal to noise ratio providing competitive advantage. Micro-wire electrodes have been extensively used for acute and chronic applications of neural recording. However, they are assembled from discrete components and prove challenging to integrate with circuitry. For brain machine interfaces, the ultimate application of a fully implantable device warrants the need for integration between the amplifiers and electrode arrays.Application
Neural recording device for development of a set of neurotherapeutic devices that computer control prosthetic limbs and devices
Advantages
- Flexible cable design alleviates strain from external connector minimizingchronic tissue damage and patient complications
- Electrodes are designed to pierce through neural tissue during implantationsurgery without buckling
- Metal traces and corresponding bond sites can be made to any size specifica-tion and spacing distance via photolithography and thus can be used inmultiple custom application-specific-integrated circuits
Technology
A flexible substrate microelectrode array has been designed using micro-fabrication techniques and tested in vivo. The neural probe array consists of eight probes with gold-plated electrode sites on the tip that protrude from a flexible cable. The benefits of the micro-fabrication design allows for tailoring the electrode geometry for neuronal structures of interest. High channel count arrays are constructed by layering the proposed design. The flexible cable additionally provides strain relief from the fixed external connection, which will minimize tissue damage from external forces. Due to the adaptability of the fabrication process metals such as platinum may be readily incorporated.
- *IP Issue Date
- May 1, 2012
- *IP Publication Date
- Dec 3, 2009
- *Principal Investigation
-
Name: Toshikazu Nishida
Department:
Name: Erin E Patrick
Department:
Name: Justin Sanchez
Department:
- 附加資料
- Inventor: Chen, Genda | Drewniak, James L. | Mu, Huimin | Pommerenke, David
Priority Number: US7421910B2
IPC Current: G01L000104
US Class: 073862451 | 340665
Assignee Applicant: The Curators of the university of Missourilumbia
Title: Strain sensitive coax cable sensors for monitoring structures
Usefulness: Strain sensitive coax cable sensors for monitoring structures
Summary: For use in electrical time domain transmission or electrical time domain reflectometry system to detect and measure strain in associated structure e.g. building, bridge, road, dam.
Novelty: Strain sensitive coax cable sensor for monitoring structure, has deformation unit associated with outer conductor to create localized deformation that creates electrically detectable inductance change with respect to outer conductor
- 主要類別
- 建築/建設
- 細分類別
- 建設工程
- 申請日期
- Sep 10, 2007
- 申請號碼
- 8,170,638
- 其他
-
- 國家/地區
- 美國
