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Cerebral blood volume mapping software for diagnosis and monitoring of brain disorders

總結

This technology is an fMRI software toolkit that quantitatively maps cerebral blood volume (CBV) for diagnosis, drug discovery, and drug efficacy testing.

技術優勢

Semi-automated program for calculation of cerebral blood volume from fMRI imagesGenerates a functional map of multiple regions in the brain Calculates statistics to quantify brain function Can be run on any Linux computer with MATLAB and modest hardware (>2 GHz quad core, 16 GB RAM, 500 GB hard drive)Can be easily implemented in existing MRI facilities

技術應用

Diagnosis of cerebral pathologiesMonitoring changes in cerebral healthPredicting patients at risk for advanced forms of psychiatric disease Drug discovery, monitoring, and efficacy testing Neurology research of the cellular and molecular pathways involved in cerebral pathologies

詳細技術說明

None

*Abstract

None

*Inquiry

Jerry KokoshkaColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR

CU14249

*Principal Investigation

*Publications

Khan UA, Liu L, Provenzano FA, Berman DE, Profaci CP, Sloan R, Mayeux R, Duff KE, Small SA. “Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer’s disease” Nat Neurosci. 2014 Feb;17(2):304-11.Moreno H, Hua F, Brown T, Small S. “Longitudinal mapping of mouse cerebral blood volume with MRI.” NMR Biomed. 2006 Aug;19(5):535-543.Tech Ventures Reference:IR CU14249Licensing Contact: Jerry Kokoshka

國家/地區

美國