Identification of stem cells as the cellular basis of prostate cancer provides therapeutic potential
- 總結
- Michael M. Shen, Ph.D..
- 技術優勢
- Previously unidentified stem cell type in prostate endothelium Stem cell type is physiologically relevant to human prostate cancerExhibits oncogenic properties faithful to disease phenotype Patent information:Patent Pending (US20110045053)Tech Ventures Reference: IR 2624
- 技術應用
- Diagnosis of prostate cancer and prostate cancer riskPotential target for the development of therapeutics for prostate cancerBasis of in vitro high throughput assays for drug and biomarker development
- 詳細技術說明
- Michael M. Shen, Ph.D..
- *Abstract
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None
- *Inquiry
- Peter GolikovColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
- *IR
- 2624
- *Principal Investigation
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- *Publications
- Wang X, Kruithof-de Julio M, Economides KD, Walker D, Yu H, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM. "A luminal epithelial stem cell that is a cell of origin for prostate cancer." Nature. 2009 Sep 24;461(7263): 495-500.Wang ZA, Toivanen R, Bergren SK, Chambon P, Shen MM. "Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer." Cell Rep. 2014 Aug 27; S2211-1247(14): 00661-5
- 國家/地區
- 美國
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