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Micro-scale pillared surfaces with variable rigidity to monitor cellular responses

總結
This technology is a lithographic technique to pattern surfaces with microscale pillars of varying rigidity to monitor cellular responses to various culture surfaces.
技術優勢
Precise control of micropillar rigidity through electron beam exposureConsistent pillar dimensions while varying rigidityCell differentiation controlled at the micro-levelNon-invasiveBiocompatible polymers
技術應用
Stem cell researchMicrochip construction and designMEMS/NEMS fabrication
詳細技術說明
None
*Abstract
None
*Inquiry
Beth KaudererColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
m08-073
*Principal Investigation
*Publications
Biggs MJP, Fernandex M, Thomas D, Cooper R, Palma M, Liao J, Fazio T, Dahlberg C, Wheadon H, Pallipurath, A, Pandit A, Kysar J, Wind SJ. “The Functional Response of Mesenchymal Stem Cells to Electron-Beam Patterned Elastomeric Surfaces Presenting Micrometer to Nanoscale Heterogeneous Rigidity”. Adv. Mater. 2017 Sept 1; 29(39): 1702119Tech Ventures Reference:IR M08-073Licensing Contact: Beth Kauderer
*Web Links
WIPO: WO/2009/123739
國家/地區
美國

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