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Flexible and rapid method for detecting and isolating human malignant cells

總結: Malignant cancer cell detection is a key factor in effective cancer diagnosis and research. However, current methods for malignancy identification are generally expensive and time-consuming, thereby creating an unmet need for a rapid and relatively inexpensive method for detecting human malignant cells in vivo, as well as in vitro. This technology provides a method for detecting the presence of human malignant cells in a sample of tumor cells. In addition, the technology also provides a method for obtaining an enriched population of live human malignant cells. As such, the technology provides a diagnostic for both detecting and isolating malignant cancer cells in tumors in vivo and in vitro.

技術優勢: Allows flexible application for a variety of malignancies. Inexpensive.Adaptable to complement a wide range of available cell detection and isolation methods.Allows rapid diagnostic and sample enrichment response.Patent information:Patent Issued (US 7,232,891)Tech Ventures Reference: IR 379

技術應用: Determining the malignancy of human tumors. Detecting malignant cells in human tumors in diagnostic assays, both in vivo and in vitro.Isolating malignant cells from a cell population for research use or for therapeutic applications.

*Inquiry: Cynthia LangColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*Publications: Krichevsky A, Campbell-Acevedo EA, Tong JY, Acevedo HF. "Immunological detection of membrane-associated human luteinizing hormone correlates with gene expression in cultured human cancer and fetal cells" Endocrinology. 1995 Mar;136(3):10349.

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