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Hand-held Collagen Imaging Device

技術優勢

Histopathologicalstudy is the gold test for clinical diagnosis, but requires biopsy and canneither be done in vivo nor in real time. UML imaging method is capable ofrapid noninvasive assessment of large skin areas in vivo and is entirelyharmless and nonintrusive. Compared to microscopy techniques, such asconfocal, two photon and second harmonic, UML imaging method provides orders ofmagnitude larger field of view combined with sufficient lateral resolution of15 μm and excellent signal to noise ratio, does not require expensivecomponents and high power densities of light exposure or laser sources.

詳細技術說明

A Hand-held device for getting clear and distinct collagen images to check on the health of skin.

*Abstract

The present invention relates to systems and methods or wide-field polarized imaging of the skin. This technology provides quantitative characterization of collagen structures in the skin and can be used to monitor skin treatment. It can be used as a handheld imaging device that generates polarized images at different depths beneath a dermal surface and a data processor to process image data.

*Background

Skin diseasesand degeneration is related to sun exposure, working environment and personalhabits, which can be observed in the change of internal structure of skin.Collagen, which is the major component of the dermal structure, is an importantfactor related to dermal changes.It is criticalto inspect collagen structure and quantitatively define status of skin.Histopathological and immune-histochemical studies are commonly used fordiagnosing diseases and evaluating dermal changes. But these techniques requirebiopsy, which may cause scarring and infection and cannot be performed eitherin vivo or in real time. Collagen content is also a good marker for assessingclinical efficacy of non-ablative fractional treatment (for skin rejuvenation).

*IP Issue Date

None

*IP Type

Other Patent

國家

United States

申請號碼

WO 2014/165820

國家/地區

美國