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Creating Chiral Organoalanes and Organic Derivatives

總結
Researchers at Purdue University have developed a method that uses Zr-catalyzed asymmetric carboalumination of alkenes to produce chiral alkylalanes. These chiral alkylalanes can then be converted to various chiral organic compounds, such as isoalkyl alcohols and other organic compounds of interest, which can then be used in the production of vitamins, pharmaceuticals, and other medicinally and biologically important compounds. This process also yields isoalkyl alcohols with a high enantiomeric excess (e.e.), often exceeding 95% e.e.
技術優勢
Can be used in production of various organic compounds of interestYields isoalkyl alcohols with high enantiomeric excess
技術應用
Chemical AnalysisPhamaceuticalsMedical/Healthcare
詳細技術說明
Ei-ichi NegishiPurdue Chemistry
*Abstract

*Background
Catalytic enantioselective carbon-carbon bond formation is a highly desirable but difficult synthetic task when it involves simple alkenes without heteroatom function groups.
*IP Issue Date
Dec 14, 1999
*IP Type
Utility
*Stage of Development
Process Validation in Lab
*Web Links
Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipEi-ichi NegishiPurdue Chemistry
國家
United States
申請號碼
6,002,037
國家/地區
美國

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