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Matrix-Free system for generating 3D cell spheroids

技術優勢

ΓÇó System can be prepared as-ready to the consumer or as a kit using consumables ΓÇó System can be adapted to many different growth environments including large culture vessels for scale-up or multi-well plates for high-throughput screeningΓÇó Utilization of the system is simple, requiring only a 1-page protocol ΓÇó System is low costΓÇó System has already received press, as part of a cover story in Genetic Engineering and Biotechnology News (GEN, June 01 issue, 2013)ΓÇó The system can be utilized for short-term as well as long-term studies (21 days or more), providing distinct advantages over 2D cell culture.ΓÇó The system provides a product in a high-growth area (3D cell culture)ΓÇó The system can be combined with high-quality optical environments to leverage emerging 3-dimensional and 4-dimensional imaging technologiesΓÇó Provides novel approaches to screen emerging nano-materials

技術應用

ΓÇó Drug screening (anti-cancer drugs)ΓÇó Tissue engineering (stem cells and normal cells)ΓÇó Diagnostics (combined 3D cell culture with sensors and fluidic devices)ΓÇó Market shares in basic research applications as well research and development in commercial areas is anticipated ΓÇó Diffusion and growth modeling in normal and diseased tissues

詳細技術說明

ΓÇó The system generates 3-dimensional (3D) cell aggregate spheroidsΓÇó No matrix or scaffold is needed; thus cells can be grown in their native mediaΓÇó System has been used to generate 3D spheroids from normal cells, stem cells, and cancer cells, from both human cells as well as from animal cells

*Abstract

Method for culturing cells three dimensionally.

*Principal Investigation

Name: Mark DeCoster, Assoc Prof

Department: Biomed Eng

國家/地區

美國