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Reusable enzyme-peptide nanoparticles for carbon dioxide capture

總結: This technology offers the best features of both free and immobilized enzymes. The carrier-free enzyme particles maintain high activity and at the same time are easily recovered for reuse. This offers the potential to significantly reduce costs for pharmaceutical, cosmetic and food processing applications.

技術優勢: - Cost-effective
- Retains catalytic performance
- No chemical functionalisation
- No support required
- Recombinantly produced at high yield
- Easy recovery and reuse

技術應用: Improved use of enzymes in pharmaceutical and fine chemical industries where an efficient, reusable and cost-effective biocatalyst is required.

詳細技術說明: A platform technology has been developed to form active enzyme nanoparticles that are 20 to 100 times larger than the free enzyme. These particles can be recovered by membrane filtration technology, enabling their reuse. A self-assembly peptide is expressed together with the enzyme of choice in a single construct and under controllable assembly conditions, spontaneously forms nanoparticles. The technology provides industry with reusable biocatalysts at low cost without the need for chemical reagents. The enzyme nanoparticles can be easily integrated into current enzyme reaction processes, resulting in a final product that is free of enzymes. Benefits:
- Recombitant expression-based production of enzymes
- Enzme purification and nanoparticle formation in a single step
- No compromise in enzyme performacex
- Large szie allows sepration using a membrance filtraion system.

其他: Monash seeks a commercial partner to licence this technology. We envisage implementing the technology into banknote production and labels for protection of high value items.

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