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A mTOR-independent Activator of TFEB for Autophagy Enhancement and Uses thereof

標題
A mTOR-independent Activator of TFEB for Autophagy Enhancement and Uses thereof
總結
This invention relates to a composition comprising an autophagy enhancement compound. In particular, the present invention relates to a composition comprising a small molecule being able to enhance autophagy and lysosome biogenesis by activating the gene TFEB which can prevent the accumulation of toxic protein aggregates in treating neurodegenerative diseases such as Parkinson's, Alzheimer's and Huntington's diseases.
技術優勢
Prevent the accumulation of toxic protein aggregates in treating neurodegenerative diseases
申請日期
1) 6 March 2015 (CN)
2) 6 March 2015 (EP)
3) 6 March 2015 (PT)
4) 30 January 2015 (US non -provisional)
5) 16 March 2016 (US non-provisional)
申請號碼
1) CN 201580012376.7
2) EP 15759224.7
3) PCT/CN2015/073764
4) US 14/609,438
5) US 15/071,222
覆蓋範圍
A small molecule being able to enhance autophagy and lysosome biogenesis by activating the gene TFEB

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