Device for Removal of Amylase from Body Fluids (Yissum)
Saliva is an easily obtainable body fluid to use when searching for disease biomarkers, hormones etc.
Amylases constitute 60% of saliva fluids and mask the presence of other protein components
Device removes amylase from oral and other body fluids to increase efficiency of analysis for other proteins . The device also enables if desired to obtain the amylase separately for any desired purpose
Working prototype completed; characterization of results obtained from device neededDevice that removes amylase from saliva and other body fluids, such as sweat, lacrimal, gastro-intestinal, and pancreatic fluids, serum and urine. The device also enables to obtain the amylase separately
Low-cost, durable, easy-to-use device
Provides higher volume of sample for analysis
Removes broad spectrum of amylase
Removes fluid debris, eliminating need for pre-separation treatment of samplez
Possible applications in biomarker discovery, clinical trials and molecular diagnostics
Biomarkers reduce time and cost for Phase I and II clinical trials by replacing clinical endpoints, producing over $200 million in revenue in 2007 and expected to quintuple in the next four years
Biomarkers promise a smoother integration of diagnostics and therapeutics
Biomarkers required for personalized medicine
7-2007-1807
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