A DIAGNOSTIC ASSAY FOR THE HUMAN VIRUS CAUSING SEVERE ACUTE RESPIRATORY SYNDROME (SARS)
The present invention relates to a diagnostic assay for the virus causing Severe Acute Respiratory Syndrome (SARS) in humans ("hSARS virus"). In particular, the invention relates to a real-time quantitative PCR assay for the detection of hSARS virus using reverse transcription and polymerase chain reaction. Specifically, the quantitative assay is a TaqMan<(R)> assay. The invention further relates to a diagnostic kit that comprises nucleic acid molecules for the detection of the hSARS virus.
Inventor: CHAN, KWOKHUNG | GUAN, YI | NICHOLLS, JOHN MALCOLM | PEIRIS, JOSEPH SRIYAL MALIK | POON, LITMAN | YUEN, KWOKYUNG | LEUNG, FREDERICK C
Priority Number: CN101186920A
IPC Current: C12N001550 | A61K0039215 | A61P001100 | A61P003114 | C07K0014165 | C07K001600 | C12Q000168 | C12Q000170 | G01N0033569
Assignee Applicant: The University of Hong Kong
Title: High-throughput diagnostic assay for the human virus causing severe acute respiratory syndrome (SARS) | High-throughput diagnostic test on human virus causing severe acute respiratory syndrome (SARS)
Usefulness: High-throughput diagnostic assay for the human virus causing severe acute respiratory syndrome (SARS) | High-throughput diagnostic test on human virus causing severe acute respiratory syndrome (SARS)
Summary: The nucleic acid molecule and polypeptide, methods, and kit are useful diagnosing and monitoring the spread of SARS. The vaccine and pharmaceutical compositions are useful for treating SARS.
Novelty: New nucleic acid molecule encoding nucleocapsid- or spike-gene protein of a human Severe Acute Respiratory Syndrome (hSARS) virus, useful for diagnosing and treating SARS
生物醫學
病原
香港
