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Method for Microbiological Quasi-Chemical Kinetics Growth-Death Modeling in Food

技术优势
· Determinesthe microbial population changes based on biochemical factors. · Predictsthe shelf life of foods and/or the microbial growth cycles on surfaces orfoods.  · Can be used to predict howor whether a particular microbial population will evolve in time.
详细技术说明
Method for ModelingGrowth-Death Kinetics in Food
*Abstract

Thisinvention relates to the field of predictive modeling to ensure themicrobiological safety and extended shelf life of foods; additionally, to aquasi-chemical mathematical modeling method which is used as a tool forpredictive microbiology evaluation of microorganism population dynamics basedon an understanding of chemical reaction pathways that are intrinsic to theseorganisms in support of the safe design of food product formulation and foodprocessing conditions.

Topredict the ideal conditions for modeling, we looked into how bacteriapopulations grow and die in response to the factors influencing a foodproducts. Intrinsic factors of the food include physical properties such as pH,water activity, salinity, and the presence of anti-microbial constituents.Extrinsic factors are also considered, which refer to properties of theexternal environment, such as storage temperature, relative humidity, ambientpressure, and applied processing conditions, all of which influence microbialsurvivability.

Currentprediction models for analyzing bacterial population dynamics turned toequations developed previously from theories of treating human and animalpopulation dynamics in their effort to model microorganism growth curves anddeath curves. These models were characterized by parameters such as per capitabirth rate, sustainable population, which are not useful for describing thegrowth and death of unicellular microorganisms. Missing from the current prediction models are criteria that evaluate ina manner that reflects the underlying biochemical and biological bases of thesechanges.

Thistechnology addresses the biochemical reasons underlying changes in microbialpopulation dynamics. The Quasi-chemical model is a mechanistic basedmathematical model that applies appropriate sequences of chemical reactions orbiochemical processes to more accurately and meaningfully represent themolecular mechanisms of bacterial anabolism, catabolism, cellular signaling(i.e. quorum sensing) and lethality that result in growth-death behavior andoffers several technological advantages over anthropomorphic models invokes byearly investigators or other empirical models currently in use. In predictivemicrobiology, predicative models provide food technologists and non-mathematicalexperts with convenient food safety tools to determine the survivability ofmicroorganisms in response to food formulations designed to control growth orin response to process conditions intended to limit or destroy pathogenicbacterial populations wherever they may originate. The data characteristic ofbacterial population dynamics are collected, characterized, and referred to interms of quantitative parameters using mathematical models or equations.

This information can be used to predict how or whetherthe microbial population will evolve in time, and will be particularlybeneficial for food shelf life safety analysis.

*IP Issue Date
None
*IP Type
Other Patent
国家
Not Available
申请号码
None
国家/地区
美国

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