Media.Player

2-Acetyl-1,3-Cyclopentanedione for the Treatment of Metabolic Disorders

技术优势

Prevents development of the diseaseDiminishes the pre-existing presence of the disease

技术应用

Treatment of obesity. diabetes mellitus, metabolic syndrome, healthcare, pharmaceutical industires

详细技术说明

Our inventors have successfully discovered 2-acetyl-1,3-cyclopentanedione (ACDP); ACPD has the potential to completely prevent development of, or reverse or diminish the pre-existing presence of, the diseases aforementioned. The technology is a novel, highly specific, potent, small molecular weight inhibitor of both atypical PKCs, PKC-zeta and PKC-lambda/iota. Effective treatment by a single agent for these abnormalities is promising for treating what is considered the major health concern of modern day; the obesity, metabolic syndrome, type 2 diabetes pandemic that constitute much of the cardiovascular disease.

*Abstract

At the University of South Florida we have recently discovered that use of small molecular weight inhibitors of protein kinase C-zeta and protein kinase C-Lambda/Iota for treatment of obesity, the metabolic syndrome, diabetes mellitus, and related hypertriglyceridemia, hypercholesterolemia and hepatosteatosis.

国家/地区

美国