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Logical Operations in Mass Spectrometry

总结

Researchers at Purdue University have developed a new methodology for operating a mass spectrometer that provides efficient routes from the large block of MS/MS data to answer particular structural questions. It is a major conceptual extension of MS/MS that allows experiments which explore the 3-dimensional data domain of MS/MS. Only data space relevant to the question is explored, minimizing time and ion utilization. This methodology is particularly valuable for ion traps and miniature in situ mass spectrometers, but the concepts could readily be extended to other types of mass spectrometers including triple quadrupoles.

技术优势

Extends power of MS/MS experimentsProvides more options to explore data spaceMinimizes time and ion utilization

技术应用

Miniature instrumentsIon trapsMulti-analyzer instruments

详细技术说明

R. Graham CooksPurdue ChemistryAston Labs

*Abstract

None

*Background

The information in tandem mass spectrometry (MS/MS) is a three-dimensional data domain which, as of right now, can only be accessed by zero or 1-dimensional experiments that explore a 2-dimensional data domain. These traditional MS/MS scans might require the sampling of multiple ion populations to answer structural questions. A method that could explore a 3-dimensional data domain following a single ion injection event would provide more options to explore the data space.

*IP Issue Date

None

*IP Type

Provisional

*Stage of Development

Process Validation in Lab

*Web Links

Purdue Office of Technology CommercializationPurdue Innovation and EntrepreneurshipR. Graham CooksPurdue ChemistryAston Labs

国家

United States

申请号码

None

国家/地区

美国